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| Nomenclature |
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Symbol:
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Spasttm1.1Jme
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Name:
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spastin;
targeted mutation 1.1, Judith Melki
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MGI ID: |
MGI:3698038 |
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Synonyms: |
Spdelta |
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Gene:
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Spast
Location:
Chr17:74338987-74391113 bp, + strand
Genetic Position: Chr17,
45.64 cM, cytoband E3
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:117740
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Intragenic deletion |
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Exons 5-7 were removed via cre-mediated excision. (J:117740)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Spast Mutation:
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7 strains or lines available |
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| References |
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Original: |
J:117740
Tarrade A et al.,
"A mutation of spastin is responsible for swellings and impairment of transport in a region of axon characterized by changes in microtubule composition."
Hum Mol Genet 2006 Dec 15;15(24):3544-58
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All: |
2 reference(s)
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Analysis Tools
