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| Nomenclature |
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Symbol:
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Casp8tm1Hed
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Name:
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caspase 8;
targeted mutation 1, Stephen M Hedrick
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MGI ID: |
MGI:3696985 |
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Synonyms: |
Casp8fl |
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Gene:
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Casp8
Location:
Chr1:58795374-58847503 bp, + strand
Genetic Position: Chr1,
29.19 cM, cytoband B
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:116713
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Exon 3 was flanked with loxP sites by homologous recombination. (J:116713)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Casp8 Mutation:
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4 strains or lines available |
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| References |
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Original: |
J:116713
Beisner DR et al.,
"Cutting edge: innate immunity conferred by B cells is regulated by caspase-8."
J Immunol 2005 Sep 15;175(6):3469-73
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All: |
8 reference(s)
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Analysis Tools
