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| Nomenclature |
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Symbol:
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Tg(Kdr-AGER)102Hyam
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Name:
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transgene insertion 102, Hiroshi Yamamoto
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MGI ID: |
MGI:3696984 |
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Synonyms: |
RAGETg |
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Transgene:
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Tg(Kdr-AGER)102Hyam
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6J x CBA/J)F1
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The mouse Kdr promoter (0.9 kb) and the 3.4 kb fragment containing the entire exonic and intronic region of the human AGER gene were ligated in the correct orientation and injected into fertilized oocytes. 6 founders were generated. Lines 102 and 103 had high expression and were used for further studies. (J:70495)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:70495
Yamamoto Y et al.,
"Development and prevention of advanced diabetic nephropathy in RAGE-overexpressing mice."
J Clin Invest 2001 Jul;108(2):261-8
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All: |
2 reference(s)
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Analysis Tools
