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| Nomenclature |
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Symbol:
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Foxp3tm1Tch
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Name:
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forkhead box P3;
targeted mutation 1, Talal A Chatila
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MGI ID: |
MGI:3696705 |
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Synonyms: |
Foxp3-, Foxp3K276X |
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Gene:
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Foxp3
Location:
ChrX:7579676-7595243 bp, + strand
Genetic Position: ChrX,
3.41 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:117165
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Parent Cell Line:
| RW-4 (ES Cell) |
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Strain of Origin:
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129X1/SvJ
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Single point mutation |
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Mutation details: A vector was designed to change codon K276 to a stop codon in exon 8. A neo included in the vector was subsequently removed via cre mediated recombination. (J:117165)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:117165
Lin W et al.,
"Allergic dysregulation and hyperimmunoglobulinemia E in Foxp3 mutant mice."
J Allergy Clin Immunol 2005 Nov;116(5):1106-15
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All: |
9 reference(s)
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Analysis Tools
