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| Nomenclature |
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Symbol:
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Tg(Syn1-ADCY7)11004Btab
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Name:
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transgene insertion 11004, Boris Tabakoff
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MGI ID: |
MGI:3695128 |
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Synonyms: |
Adcy7huTG |
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Transgene:
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Tg(Syn1-ADCY7)11004Btab
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x SJL)F2
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: This transgene consists of a 4.5 kb fragment of the rat synapsin I promotor, a 3.6 kb fragment of human ADCY7 cDNA, and a 650 bp fragment of the human growth hormone gene. Expression is confined to the central nervous system. Three lines (11004, 11012, and 10115) with high levels of expression were created which all have identical phenotype. One of these lines (10115) was generated using FVB/N oocytes while the other 2 used hybrid C57BL/6 x SJL oocytes. This is a representative record for all three lines (J:116797)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:116797
Yoshimura M et al.,
"Overexpression of type 7 adenylyl cyclase in the mouse brain enhances acute and chronic actions of morphine."
Mol Pharmacol 2000 Nov;58(5):1011-6
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All: |
2 reference(s)
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Analysis Tools
