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| Nomenclature |
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Symbol:
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Tg(tetO/CMV-KRAS*G12C)9.1Msmi
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Name:
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transgene insertion 9.1, Mark Miller
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MGI ID: |
MGI:3693226 |
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Synonyms: |
Ki-rasG12C |
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Transgene:
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Tg(tetO/CMV-KRAS*G12C)9.1Msmi
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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FVB/NTac
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: A genomic segment including the KRASG12C mutation was cloned from the H358 human lung bronchioalveolar cell line and placed under the regulation of a tetracycline-inducible (tetO)/cytomegalovirus (CMV) promoter. Copy number is estimated at 22. (J:102839)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:102839
Floyd HS et al.,
"Conditional expression of the mutant Ki-rasG12C allele results in formation of benign lung adenomas: development of a novel mouse lung tumor model."
Carcinogenesis 2005 Dec;26(12):2196-206
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All: |
4 reference(s)
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Analysis Tools
