|
|
| Nomenclature |
|
Symbol:
|
Satb2tm1Rug
|
|
Name:
|
special AT-rich sequence binding protein 2;
targeted mutation 1, Rudolf Grosschedl
|
|
MGI ID: |
MGI:3692768 |
|
Synonyms: |
Satb2-, Satb2LacZ |
|
Gene:
|
Satb2
Location:
Chr1:56793986-56978650 bp, - strand
Genetic Position: Chr1,
28.72 cM
|
|
Mutation origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:115876
|
|
Parent Cell Line:
| Not Specified (ES Cell) |
|
Strain of Origin:
|
Not Specified
|
|
Mutation description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: A betagalactosidase/pgk-neo cassette was inserted in frame with the ATG codon in exon 2. Immunoblot confirmed absence of protein in mutant mice. (J:115876)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Satb2 Mutation:
|
6 strains or lines available |
|
| References |
|
Original: |
J:115876
Dobreva G et al.,
"SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation."
Cell 2006 Jun 2;125(5):971-86
|
|
All: |
5 reference(s)
|
|