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| Nomenclature |
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Symbol:
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Jag1tm2Grid
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Name:
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jagged 1;
targeted mutation 2, Tom Gridley
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MGI ID: |
MGI:3692444 |
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Synonyms: |
Jag1flox |
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Gene:
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Jag1
Location:
Chr2:137081456-137116644 bp, - strand
Genetic Position: Chr2,
67.73 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:115783
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Parent Cell Line:
| CJ7 (ES Cell) |
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Strain of Origin:
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129S1/Sv-Oca2+ Tyr+ Kitl+
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Mutation description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Exon 4 was flanked by loxP sites. An FRT-flanked neo was removed from the locus. (J:115783)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:115783
Kiernan AE et al.,
"The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner ear."
PLoS Genet 2006 Jan;2(1):e4
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All: |
6 reference(s)
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