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| Nomenclature |
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Symbol:
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Cd151tm1Son
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Name:
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CD151 antigen;
targeted mutation 1, Arnoud Sonnenberg
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MGI ID: |
MGI:3691076 |
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Synonyms: |
Cd151- |
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Gene:
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Cd151
Location:
Chr7:141467362-141471479 bp, + strand
Genetic Position: Chr7,
86.82 cM
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Glomerular basement membrane abnormalities and foot process effacement in kidneys of mildly affected Cd151tm1Son/Cd151tm1Son and Itga3tm1Son/Itga3tm1Son Tg(NPHS2-cre)295Lbh/0 mice
Show the 3 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:114988
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Intragenic deletion |
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Mutation details: Exons 2-4 were removed via cre mediated recombination. Immunoblot failed to detect protein in mutant MEFs (J:114988)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Cd151 Mutation:
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19 strains or lines available |
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| References |
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Original: |
J:114988
Sachs N et al.,
"Kidney failure in mice lacking the tetraspanin CD151."
J Cell Biol 2006 Oct 9;175(1):33-9
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All: |
3 reference(s)
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Analysis Tools
