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| Nomenclature |
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Symbol:
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Fkbp4tm1Shou
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Name:
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FK506 binding protein 4;
targeted mutation 1, Weinian Shou
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MGI ID: |
MGI:3690438 |
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Synonyms: |
Fkbp52- |
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Gene:
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Fkbp4
Location:
Chr6:128429735-128438677 bp, - strand
Genetic Position: Chr6,
63.0 cM
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Abnormal male reproductive anatomy in Fkbp4tm1Shou/Fkbp4tm1Shou mice
Show the 2 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:114715
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Parent Cell Line:
| CCE916 (ES Cell) |
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Strain of Origin:
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129S/SvEv
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exons 2-5 were replaced with a PGK-neo cassette. Northern and Western blot confirmed that the expression was absent in mutant mice. (J:114715)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Fkbp4 Mutation:
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11 strains or lines available |
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| References |
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Original: |
J:114715
Yang Z et al.,
"FK506-binding protein 52 is essential to uterine reproductive physiology controlled by the progesterone receptor a isoform."
Mol Endocrinol 2006 Nov;20(11):2682-94
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All: |
3 reference(s)
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Analysis Tools
