|
|
| Nomenclature |
|
Symbol:
|
Lcktm1Dbs
|
|
Name:
|
lymphocyte protein tyrosine kinase;
targeted mutation 1, David B Straus
|
|
MGI ID: |
MGI:3690319 |
|
Synonyms: |
lckW97A |
|
Gene:
|
Lck
Location:
Chr4:129548349-129573641 bp, - strand
Genetic Position: Chr4,
63.26 cM, cytoband distal
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:114660
|
|
Parent Cell Line:
| Not Specified (ES Cell) |
|
Strain of Origin:
|
Not Specified
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-in) |
|
Mutation: | |
Nucleotide substitutions |
| |
|
The W97A mutation was inserted into exon 3. (J:114660)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Lck Mutation:
|
38 strains or lines available |
|
| References |
|
Original: |
J:114660
Rudd ML et al.,
"Lck SH3 domain function is required for T-cell receptor signals regulating thymocyte development."
Mol Cell Biol 2006 Nov;26(21):7892-900
|
|
All: |
2 reference(s)
|
|
Analysis Tools
