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| Nomenclature |
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Symbol:
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Tg(Myh6-PRKAG2*R302Q)#Rro
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Name:
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transgene insertion #, Robert Roberts
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MGI ID: |
MGI:3688892 |
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Synonyms: |
TGR302Q |
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Transgene:
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Tg(Myh6-PRKAG2*R302Q)#Rro
Location:
unknown
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Transgene origin |
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Transgene description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: This transgene consists of the human PRKAG2 cDNA with a substitution of an arginine for glutamine at amino acid residue 302 under the control of the cardiac specific alpha-myosin heavy chain promoter. Expression of the transgene was confirmed by Northern analysis. Three lines were made but the reference does not distinguish between them. Data may have been pooled from more than one line. (J:108102)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:108102
Sidhu JS et al.,
"Transgenic mouse model of ventricular preexcitation and atrioventricular reentrant tachycardia induced by an AMP-activated protein kinase loss-of-function mutation responsible for Wolff-Parkinson-White syndrome."
Circulation 2005 Jan 4;111(1):21-9
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All: |
1 reference(s)
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