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| Nomenclature |
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Symbol:
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Tg(Myh6-PRKAG2*R531G)22Dca
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Name:
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transgene insertion 22, David Carling
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MGI ID: |
MGI:3688831 |
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Synonyms: |
RG-TG22 |
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Transgene:
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Tg(Myh6-PRKAG2*R531G)22Dca
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/10 x CBA/Ca)F1
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: This transgene consists of the human Prkag2 cDNA, with a point mutation altering arginine 531 to glycine, under the control of the cardiac-specific alpha-myosin heavy chain promoter. Western blot analysis of heart lysates confirmed that protein expression is restricted to the heart. (J:108517)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:108517
Davies JK et al.,
"Characterization of the role of gamma2 R531G mutation in AMP-activated protein kinase in cardiac hypertrophy and Wolff-Parkinson-White syndrome."
Am J Physiol Heart Circ Physiol 2006 May;290(5):H1942-51
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All: |
1 reference(s)
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Analysis Tools
