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| Nomenclature |
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Symbol:
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Nlgn3tm1Bros
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Name:
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neuroligin 3;
targeted mutation 1, Nils Brose
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MGI ID: |
MGI:3687640 |
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Gene:
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Nlgn3
Location:
ChrX:101299168-101325963 bp, + strand
Genetic Position: ChrX,
43.95 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:113647
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neo was inserted into the locus to replace the exon encompassing the translational start site at 574 bp. Western blot confirmed absence of full length and truncated protein in these mutants.
(J:113647)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Nlgn3 Mutation:
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14 strains or lines available |
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| References |
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Original: |
J:113647
Varoqueaux F et al.,
"Neuroligins determine synapse maturation and function."
Neuron 2006 Sep 21;51(6):741-54
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All: |
3 reference(s)
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