|
|
| Nomenclature |
|
Symbol:
|
Nlgn2tm1Bros
|
|
Name:
|
neuroligin 2;
targeted mutation 1, Nils Brose
|
|
MGI ID: |
MGI:3687639 |
|
Synonyms: |
NL2- |
|
Gene:
|
Nlgn2
Location:
Chr11:69823122-69837784 bp, - strand
Genetic Position: Chr11,
42.89 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:113647
|
|
Parent Cell Line:
| Not Specified (ES Cell) |
|
Strain of Origin:
|
Not Specified
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Mutation details: A 380 bp fragment including the translation start site was replaced with a neo cassette via homologous recombination. Western blot confirmed absence of full length and truncated protein in whole brain homogenates from homozygous mice. (J:113647)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:113647
Varoqueaux F et al.,
"Neuroligins determine synapse maturation and function."
Neuron 2006 Sep 21;51(6):741-54
|
|
All: |
8 reference(s)
|
|
Analysis Tools
