|
|
| Nomenclature |
|
Symbol:
|
Tg(TcraBDC12-4.1)10Jos
|
|
Name:
|
transgene insertion 10, Joslin Diabetes Center
|
|
MGI ID: |
MGI:3687036 |
|
Synonyms: |
alpha10, BDC12.4 TCR alpha10 |
|
Transgene:
|
Tg(TcraBDC12-4.1)10Jos
Location:
unknown
|
|
Transgene origin |
|
Transgene description |
|
Transgene
Type: | |
Transgenic (random, expressed) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: The TCR alpha (TRAV5D-4*04/TRAJ53*01) chain from the BDC12-4.1 clone was subcloned into a TCR cassette. (J:111874)
|
|
Inheritance: | |
Dominant |
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:111874
Jasinski JM et al.,
"Transgenic insulin (B:9-23) T-cell receptor mice develop autoimmune diabetes dependent upon RAG genotype, H-2g7 homozygosity, and insulin 2 gene knockout."
Diabetes 2006 Jul;55(7):1978-84
|
|
All: |
1 reference(s)
|
|