|
|
| Nomenclature |
|
Symbol:
|
Arid4atm1Alb
|
|
Name:
|
AT rich interactive domain 4A (RBP1-like);
targeted mutation 1, Arthur L Beaudet
|
|
MGI ID: |
MGI:3687004 |
|
Synonyms: |
Arid4a- |
|
Gene:
|
Arid4a
Location:
Chr12:71015990-71098592 bp, + strand
Genetic Position: Chr12,
29.39 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:113402
|
|
Parent Cell Line:
| AB2.2 (ES Cell) |
|
Strain of Origin:
|
129S7/SvEvBrd-Hprtb-m2
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Mutation details: A vector was designed to insert a lacZ and a floxed neo into the ATG in exon 1, and replacing exon 2. RT-PCR failed to detect normal transcript in mutant mice. (J:113402)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Arid4a Mutation:
|
14 strains or lines available |
|
| References |
|
Original: |
J:113402
Wu MY et al.,
"Deficiency of Rbbp1/Arid4a and Rbbp1l1/Arid4b alters epigenetic modifications and suppresses an imprinting defect in the PWS/AS domain."
Genes Dev 2006 Oct 15;20(20):2859-70
|
|
All: |
2 reference(s)
|
|
Analysis Tools
