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| Nomenclature |
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Symbol:
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Gbx2tm1Mrt
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Name:
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gastrulation brain homeobox 2;
targeted mutation 1, Gail R Martin
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MGI ID: |
MGI:3665450 |
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Synonyms: |
Gbx2flox |
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Gene:
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Gbx2
Location:
Chr1:89927962-89933290 bp, - strand
Genetic Position: Chr1,
45.06 cM, cytoband C5-E1
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:42110
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: LoxP sites were inserted to flank exon 2, with a neo cassette upstream of the 5' loxP site. Aberrantly spliced transcripts were detected in these mutants. (J:42110)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Gbx2 Mutation:
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7 strains or lines available |
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| References |
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Original: |
J:42110
Wassarman KM et al.,
"Specification of the anterior hindbrain and establishment of a normal mid/hindbrain organizer is dependent on Gbx2 gene function."
Development 1997 Aug;124(15):2923-34
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All: |
4 reference(s)
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Analysis Tools
