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| Nomenclature |
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Symbol:
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Igh-Jtm1Aigl
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Name:
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immunoglobulin heavy chain, joining region;
targeted mutation 1, Antonio Iglesias
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MGI ID: |
MGI:3665428 |
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Synonyms: |
IgHMOG, Th |
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Gene:
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Igh-J
Location:
unknown
Genetic Position: Chr12,
Syntenic
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:111543
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutations: | |
Insertion, Intergenic deletion |
| |
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A rearranged VHDJH gene with a neo cassette replaced the locus replaced the DQ52/JH1-4 region. (J:111543)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Igh-J Mutation:
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11 strains or lines available |
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| References |
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Original: |
J:111543
Litzenburger T et al.,
"B lymphocytes producing demyelinating autoantibodies: development and function in gene-targeted transgenic mice."
J Exp Med 1998 Jul 6;188(1):169-80
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All: |
7 reference(s)
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Analysis Tools
