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| Nomenclature |
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Symbol:
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Ptch2tm1Pmc
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Name:
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patched homolog 2;
targeted mutation 1, Peter J McKinnon
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MGI ID: |
MGI:3665289 |
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Synonyms: |
Ptch2- |
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Gene:
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Ptch2
Location:
Chr4:117096075-117116101 bp, + strand
Genetic Position: Chr4,
53.41 cM, cytoband C-D
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:112118
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Parent Cell Line:
| W9.5/W95 (ES Cell) |
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Strain of Origin:
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129S1/Sv-Oca2+ Tyr+ Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Intragenic deletion |
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Mutation details: Exons 5-17 were removed from the locus by cre mediated recombination. RT-PCR confirmed absence of transcript encoded by this sequence. (J:112118)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Ptch2 Mutation:
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10 strains or lines available |
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| References |
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Original: |
J:112118
Lee Y et al.,
"Patched2 modulates tumorigenesis in patched1 heterozygous mice."
Cancer Res 2006 Jul 15;66(14):6964-71
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All: |
2 reference(s)
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Analysis Tools
