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| Nomenclature |
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Symbol:
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Elovl4tm1Sie
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Name:
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elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4;
targeted mutation 1, Paul A Sieving
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MGI ID: |
MGI:3664793 |
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Gene:
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Elovl4
Location:
Chr9:83778693-83806305 bp, - strand
Genetic Position: Chr9,
45.6 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:112264
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A 62 bp deletion in exon2 and a splice acceptor, IRES, lacZ, and PGK-neo cassette were inserted via homologous recombination. (J:112264)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Elovl4 Mutation:
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0 strains or lines available |
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| References |
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Original: |
J:112264
Raz-Prag D et al.,
"Haploinsufficiency is not the key mechanism of pathogenesis in a heterozygous Elovl4 knockout mouse model of STGD3 disease."
Invest Ophthalmol Vis Sci 2006 Aug;47(8):3603-11
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All: |
2 reference(s)
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Analysis Tools
