Col5a1<tm1Rjw> Targeted Allele Detail MGI Mouse (MGI:3664598)

Col5a1^tm1Rjw
Targeted Allele Detail

Nomenclature

Symbol:	Col5a1^tm1Rjw
Name:	collagen, type V, alpha 1; targeted mutation 1, Richard J Wenstrup
MGI ID:	MGI:3664598
Synonyms:	Col5a1^-, ColVa1-
Gene:	Col5a1 Location: Chr2:27886425-28039514 bp, + strand Genetic Position: Chr2, 19.38 cM, cytoband A2-B

E10.5 Col5a1^tm1Rjw/Col5a1^tm1Rjw embryos exhibit blood pooling and absence of blood-filled vessels in yolk sacs

Show the 8 image(s) involving this allele.

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:113133
Parent Cell Line:	KG-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Mutation
description

Allele Type:		Targeted (knock-out)
Mutations:		Insertion, Intragenic deletion
		Exon 3 and part of exon 4 were replaced with a neomycin resistance cassette. (J:113133)

Phenotypes

View phenotypes for all genotypes (concatenated display).

Disease models

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)

Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Col5a1 Mutation:	3 strains or lines available

References

Original:	J:113133 Wenstrup RJ et al., "Type V collagen controls the initiation of collagen fibril assembly." J Biol Chem 2004 Dec 17;279(51):53331-7
All:	4 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources Funding Information Warranty Disclaimer & Copyright Notice Send questions and comments to User Support.	last database update 05/08/2013 MGI 5.13