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| Nomenclature |
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Symbol:
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Hspa5tm1.1Alee
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Name:
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heat shock protein 5;
targeted mutation 1.1, Amy S Lee
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MGI ID: |
MGI:3664111 |
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Synonyms: |
Grp78- |
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Gene:
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Hspa5
Location:
Chr2:34771970-34776531 bp, + strand
Genetic Position: Chr2,
22.94 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:111416
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Intragenic deletion |
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Mutation details: A vector was designed to insert a floxed neo into intron 4 and a third loxP site into intron 7. Cre expression in the germline resulted in the excision of exons 5-7. (J:111416)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Hspa5 Mutation:
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5 strains or lines available |
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| References |
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Original: |
J:111416
Luo S et al.,
"GRP78/BiP is required for cell proliferation and protecting the inner cell mass from apoptosis during early mouse embryonic development."
Mol Cell Biol 2006 Aug;26(15):5688-97
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All: |
7 reference(s)
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Analysis Tools
