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| Nomenclature |
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Symbol:
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Gpr12tm1Dgen
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Name:
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G-protein coupled receptor 12;
targeted mutation 1, Deltagen
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MGI ID: |
MGI:3663376 |
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Synonyms: |
Gpr12- |
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Gene:
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Gpr12
Location:
Chr5:146582151-146585239 bp, - strand
Genetic Position: Chr5,
85.23 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:111942
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: An IRES-lacZ-pA-PGK-neo-pA cassette replaced a sequence of exon 2 corresponding to nucleotides 155-507. LacZ expression was visualized in mutant brain sections. (J:111942)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Gpr12 Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:111942
Bjursell M et al.,
"G protein-coupled receptor 12 deficiency results in dyslipidemia and obesity in mice."
Biochem Biophys Res Commun 2006 Sep 22;348(2):359-66
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All: |
3 reference(s)
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Analysis Tools
