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| Nomenclature |
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Symbol:
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Ctcftm1Laat
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Name:
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CCCTC-binding factor;
targeted mutation 1, Wouter de Laat
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MGI ID: |
MGI:3663291 |
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Synonyms: |
Ctcff |
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Gene:
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Ctcf
Location:
Chr8:105636568-105682922 bp, + strand
Genetic Position: Chr8,
53.04 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:112158
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A floxed neo cassette was inserted upstream of exon 3 and a floxed puromycin resistance cassette followed by a lacZ gene was inserted downstream of exon 12. (J:143271)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Ctcf Mutation:
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58 strains or lines available |
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| References |
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Original: |
J:112158
Splinter E et al.,
"CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus."
Genes Dev 2006 Sep 1;20(17):2349-54
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All: |
6 reference(s)
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