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| Nomenclature |
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Symbol:
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Slc40a1ffe
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Name:
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solute carrier family 40 (iron-regulated transporter), member 1;
flatiron
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MGI ID: |
MGI:3662903 |
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Synonyms: |
Fpnffe |
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Gene:
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Slc40a1
Location:
Chr1:45908070-45925594 bp, - strand
Genetic Position: Chr1,
23.96 cM, cytoband B
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Mutation
origin |
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Strain of Origin:
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C57BL/6J
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Mutation
description |
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Allele
Type: | |
Chemically induced (ENU) |
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Mutation: | |
Single point mutation |
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Mutation details: This allele contains an A to G transition at position 95 in the coding sequence, resulting in an H32R substitution in the signal sequence. (J:118592)
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Inheritance: | |
Dominant |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Slc40a1 Mutation:
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5 strains or lines available |
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| References |
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Original: |
J:118592
Zohn IE et al.,
"The flatiron mutation in mouse ferroportin acts as a dominant negative to cause ferroportin disease"
Blood 2007 May 15;109(10):4171-80
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All: |
3 reference(s)
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Analysis Tools
