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| Nomenclature |
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Symbol:
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Nkx2-5tm4Rph
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Name:
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NK2 transcription factor related, locus 5 (Drosophila);
targeted mutation 4, Richard P Harvey
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MGI ID: |
MGI:3655239 |
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Synonyms: |
Nkx2-5-, Nkx2-5GFP, Nkx2,5GFP |
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Gene:
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Nkx2-5
Location:
Chr17:26838664-26841565 bp, - strand
Genetic Position: Chr17,
13.6 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:81343
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Parent Cell Line:
| W9.5/W95 (ES Cell) |
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Strain of Origin:
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129S1/Sv-Oca2+ Tyr+ Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutation: | |
Insertion |
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Mutation details: Sequence encoding enhanced GFP was inserted at codon 35 of the endogenous locus via homologous recombination. (J:81343)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Nkx2-5 Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:81343
Biben C et al.,
"Cardiac septal and valvular dysmorphogenesis in mice heterozygous for mutations in the homeobox gene Nkx2-5."
Circ Res 2000 Nov 10;87(10):888-95
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All: |
10 reference(s)
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Analysis Tools
