|
|
| Nomenclature |
|
Symbol:
|
Xrcc4tm2Fwa
|
|
Name:
|
X-ray repair complementing defective repair in Chinese hamster cells 4;
targeted mutation 2, Frederick W Alt
|
|
MGI ID: |
MGI:3641440 |
|
Synonyms: |
Xc, Xrcc4c |
|
Gene:
|
Xrcc4
Location:
Chr13:89774027-90089608 bp, - strand
Genetic Position: Chr13,
45.5 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:109585
|
|
Parent Cell Line:
| TC1/TC-1 (ES Cell) |
|
Strain of Origin:
|
129S6/SvEvTac
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (Floxed/Frt) |
|
Mutation: | |
Insertion |
| |
|
LoxP sites flanked exon 3 by homologous recombination. (J:109585)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Xrcc4 Mutation:
|
12 strains or lines available |
|
| References |
|
Original: |
J:109585
Yan CT et al.,
"XRCC4 suppresses medulloblastomas with recurrent translocations in p53-deficient mice."
Proc Natl Acad Sci U S A 2006 May 9;103(19):7378-83
|
|
All: |
10 reference(s)
|
|
Analysis Tools
