|
|
| Nomenclature |
|
Symbol:
|
Plxna1tm1Kik
|
|
Name:
|
plexin A1;
targeted mutation 1, Hitoshi Kikutani
|
|
MGI ID: |
MGI:3641211 |
|
Synonyms: |
plexin-A1- |
|
Gene:
|
Plxna1
Location:
Chr6:89316316-89362613 bp, - strand
Genetic Position: Chr6,
39.91 cM, cytoband E2
|
|
Mutation origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:110786
|
|
Parent Cell Line:
| Not Specified (ES Cell) |
|
Strain of Origin:
|
Not Specified
|
|
Mutation description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Mutation details: A 3 Kb fragment containing the second exon with the intitiation codon and the third exon with the coding sequence of the Sema-domain was replaced with a neo cassette. Deletion was confirmed by northern blotting an RT-PCR. (J:110786)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Plxna1 Mutation:
|
4 strains or lines available |
|
| References |
|
Original: |
J:110786
Takegahara N et al.,
"Plexin-A1 and its interaction with DAP12 in immune responses and bone homeostasis."
Nat Cell Biol 2006 Jun;8(6):615-22
|
|
All: |
3 reference(s)
|
|