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| Nomenclature |
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Symbol:
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Cyp4a10tm1Jhc
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Name:
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cytochrome P450, family 4, subfamily a, polypeptide 10;
targeted mutation 1, Jorge H Capdevila
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MGI ID: |
MGI:3640474 |
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Gene:
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Cyp4a10
Location:
Chr4:115518264-115533649 bp, + strand
Genetic Position: Chr4,
53.05 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:110364
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Parent Cell Line:
| TL1/TL-1 (ES Cell) |
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Strain of Origin:
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129S6/SvEvTac
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A gene segment including exon 3 and part of exon 4 was replaced with a neo cassette via homologous recombination. (J:110364)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Cyp4a10 Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:110364
Nakagawa K et al.,
"Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel."
J Clin Invest 2006 Jun;116(6):1696-702
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All: |
1 reference(s)
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Analysis Tools
