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| Nomenclature |
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Symbol:
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Ptgs2tm1.1Fun
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Name:
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prostaglandin-endoperoxide synthase 2;
targeted mutation 1.1, Colin D Funk
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MGI ID: |
MGI:3629677 |
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Synonyms: |
Ptgs2Y385F, Y371F |
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Gene:
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Ptgs2
Location:
Chr1:150100124-150108010 bp, + strand
Genetic Position: Chr1,
63.84 cM, cytoband H1
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:109548
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Parent Cell Line:
| TL1/TL-1 (ES Cell) |
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Strain of Origin:
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129S6/SvEvTac
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Insertion |
| |
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Mutation details: This allele was generated by Cre mediated recombination of Ptgs2tm1Fun, resulting in the loss of the neomycin selection cassette. (J:109548)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:109548
Yu Y et al.,
"Genetic model of selective COX2 inhibition reveals novel heterodimer signaling."
Nat Med 2006 Jun;12(6):699-704
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All: |
5 reference(s)
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Analysis Tools
