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| Nomenclature |
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Symbol:
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Pcsk1N222D
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Name:
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proprotein convertase subtilisin/kexin type 1;
N222D
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MGI ID: |
MGI:3629669 |
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Synonyms: |
Pc1N222D |
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Gene:
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Pcsk1
Location:
Chr13:75089826-75132498 bp, + strand
Genetic Position: Chr13,
40.63 cM, cytoband C2
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Mutation
origin |
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Strain of Origin:
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C57BL/6
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Mutation
description |
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Allele
Type: | |
Chemically induced (ENU) |
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Mutation: | |
Single point mutation |
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An A to G transition resulted in an asparagines to aspartic acid at codon 222. (J:109531)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:109531
Lloyd DJ et al.,
"Obesity, hyperphagia and increased metabolic efficiency in Pc1 mutant mice."
Hum Mol Genet 2006 Jun 1;15(11):1884-93
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All: |
1 reference(s)
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Analysis Tools
