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| Nomenclature |
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Symbol:
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Pdpk1tm1Maka
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Name:
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3-phosphoinositide dependent protein kinase 1;
targeted mutation 1, Masato Kasuga
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MGI ID: |
MGI:3628819 |
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Synonyms: |
betaPdk1-, Pdk1flox, Pdk1tm1Maka |
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Gene:
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Pdpk1
Location:
Chr17:24073680-24150924 bp, - strand
Genetic Position: Chr17,
12.23 cM, cytoband A3.3
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:109359
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Parent Cell Line:
| J1 (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: LoxP sites were inserted to flank exons 3 and 4. Transient cre expression removed a floxed neo that was inserted into the locus. (J:109359)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:109359
Inoue H et al.,
"Role of hepatic STAT3 in brain-insulin action on hepatic glucose production."
Cell Metab 2006 Apr;3(4):267-75
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All: |
11 reference(s)
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Analysis Tools
