|
|
| Nomenclature |
|
Symbol:
|
Shox2tm1.1Ddu
|
|
Name:
|
short stature homeobox 2;
targeted mutation 1.1, Denis Duboule
|
|
MGI ID: |
MGI:3628798 |
|
Synonyms: |
Shox2- |
|
Gene:
|
Shox2
Location:
Chr3:66971727-66981771 bp, - strand
Genetic Position: Chr3,
30.76 cM, cytoband E3-F1
|
|
Limb phenotype of Shox2tm1Ddu/Shox2tm1.1Ddu Tg(Prrx1-cre)1Cjt mice
Show the 1 image(s) involving this allele.
|
 |
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:107668
|
|
Parent Cell Line:
| P1 (ES Cell) |
|
Strain of Origin:
|
129S2/SvPas
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutation: | |
Intragenic deletion |
| |
|
Cre mediated recombination resulted in deletion of the entire coding region. (J:107668)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Shox2 Mutation:
|
2 strains or lines available |
|
| References |
|
Original: |
J:107668
Cobb J et al.,
"A mouse model for human short-stature syndromes identifies Shox2 as an upstream regulator of Runx2 during long-bone development."
Proc Natl Acad Sci U S A 2006 Mar 21;103(12):4511-5
|
|
All: |
2 reference(s)
|
|
Analysis Tools
