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| Nomenclature |
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Symbol:
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Shox2tm1Ddu
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Name:
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short stature homeobox 2;
targeted mutation 1, Denis Duboule
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MGI ID: |
MGI:3626291 |
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Synonyms: |
Shox2flox, Shox2floxed |
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Gene:
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Shox2
Location:
Chr3:66971727-66981771 bp, - strand
Genetic Position: Chr3,
30.76 cM, cytoband E3-F1
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Limb phenotype of Shox2tm1Ddu/Shox2tm1.1Ddu Tg(Prrx1-cre)1Cjt mice
Show the 1 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:107668
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Parent Cell Line:
| P1 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: LoxP sites were inserted to flank the entire coding region of the locus. An FRT-flanked neo included in the vector was removed by FLP mediated recombination. (J:107668)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Shox2 Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:107668
Cobb J et al.,
"A mouse model for human short-stature syndromes identifies Shox2 as an upstream regulator of Runx2 during long-bone development."
Proc Natl Acad Sci U S A 2006 Mar 21;103(12):4511-5
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All: |
6 reference(s)
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Analysis Tools
