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| Nomenclature |
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Symbol:
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Hk2tm1Laak
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Name:
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hexokinase 2;
targeted mutation 1, Markku Laakso
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MGI ID: |
MGI:3624862 |
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Synonyms: |
HKII- |
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Gene:
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Hk2
Location:
Chr6:82725025-82774454 bp, - strand
Genetic Position: Chr6,
35.94 cM
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E8.5 Hk2tm1Laak/Hk2tm1Laak embryos are growth retarded
Show the 1 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:56644
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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A neomycin resistance cassette was inserted into exon 4. (J:56644)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:56644
Heikkinen S et al.,
"Hexokinase II-deficient mice. Prenatal death of homozygotes without disturbances in glucose tolerance in heterozygotes."
J Biol Chem 1999 Aug 6;274(32):22517-23
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All: |
4 reference(s)
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Analysis Tools
