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| Nomenclature |
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Symbol:
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Aqp2tm1Nlsn
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Name:
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aquaporin 2;
targeted mutation 1, Soren Nielsen
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MGI ID: |
MGI:3624696 |
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Synonyms: |
Aqp2flx |
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Gene:
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Aqp2
Location:
Chr15:99579056-99584545 bp, + strand
Genetic Position: Chr15,
56.13 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:108291
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129/Sv
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Mutation description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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LoxP sites were inserted into introns 2 and 3. (J:108291)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Aqp2 Mutation:
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6 strains or lines available |
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| References |
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Original: |
J:108291
Rojek A et al.,
"Severe urinary concentrating defect in renal collecting duct-selective AQP2 conditional-knockout mice."
Proc Natl Acad Sci U S A 2006 Apr 11;103(15):6037-42
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All: |
2 reference(s)
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