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| Nomenclature |
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Symbol:
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Isl1tm1(cre)Sev
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Name:
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ISL1 transcription factor, LIM/homeodomain;
targeted mutation 1, Sylvia Evans
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MGI ID: |
MGI:3623159 |
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Synonyms: |
Isl1Cre, Isl1Cre, Isl1:Cre |
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Gene:
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Isl1
Location:
Chr13:116298281-116309688 bp, - strand
Genetic Position: Chr13,
64.87 cM, cytoband D2.3
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:107396
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Insertion |
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Mutation details: A cre gene and frt-flanked neo cassette were inserted 6 bp upstream of the translation initiation codon. The neo cassette was removed by germ line, flp-mediated recombination. Expression of cre is regulated by the endogenous promoter. (J:107396)
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Recombinase activity
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Driver:
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Isl1
Summary of all recombinase alleles
driven by Isl1.
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MGI has not yet included tissue activity data for this allele in any anatomical systems.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:107396
Yang L et al.,
"Isl1Cre reveals a common Bmp pathway in heart and limb development."
Development 2006 Apr;133(8):1575-85
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All: |
22 reference(s)
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Analysis Tools
