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| Nomenclature |
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Symbol:
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Tg(INS-Il10)#Sar
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Name:
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transgene insertion #, Nora Sarvetnick
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MGI ID: |
MGI:3622661 |
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Transgene:
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Tg(INS-Il10)#Sar
Location:
unknown
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Tg(INS-Il10)#Sar/0 mice accumulate imflammatory cells within exocrine pancreatic tissue
Show the 1 image(s) involving this allele.
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: A 594-bp fragment encoding the murine Il10 was inserted behind the human insulin promoter which is in a vector also containing the termination sequence from the hepatitis B virus gene. Il10 is expressed by the islet of Langerhans cells in the pancreas. (J:107927)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:107927
Wogensen L et al.,
"Leukocyte extravasation into the pancreatic tissue in transgenic mice expressing interleukin 10 in the islets of Langerhans."
J Exp Med 1993 Jul 1;178(1):175-85
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All: |
5 reference(s)
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Analysis Tools
