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| Nomenclature |
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Symbol:
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Dkk3tm1Cni
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Name:
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dickkopf homolog 3 (Xenopus laevis);
targeted mutation 1, Christof Niehrs
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MGI ID: |
MGI:3621929 |
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Synonyms: |
Dkk3- |
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Gene:
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Dkk3
Location:
Chr7:112116019-112159057 bp, - strand
Genetic Position: Chr7,
58.74 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:106922
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129X1/SvJ
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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Mutation details: A targeting vector was designed to replace most of exon 2 with an in-frame lacZ and floxed neo cassette. Immunohistochemistry demonstrated that expression in mutants was very weak and limited to the regions of the cerebral cortex. (J:106922)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Dkk3 Mutation:
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7 strains or lines available |
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| References |
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Original: |
J:106922
Barrantes Idel B et al.,
"Generation and characterization of dickkopf3 mutant mice."
Mol Cell Biol 2006 Mar;26(6):2317-26
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All: |
4 reference(s)
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Analysis Tools
