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| Nomenclature |
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Symbol:
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Lystbg-grey
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Name:
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lysosomal trafficking regulator;
beige grey
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MGI ID: |
MGI:3620573 |
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Gene:
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Lyst
Location:
Chr13:13590409-13777440 bp, + strand
Genetic Position: Chr13,
5.28 cM
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Morphologic investigation of Lystbg-grey/Lystbg-grey and +/+ wild-type mice.
Show the 1 image(s) involving this allele.
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Mutation
origin |
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Strain of Origin:
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C57BL/6
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Mutation
description |
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Allele
Type: | |
Chemically induced (ENU) |
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Mutation: | |
Nucleotide substitutions |
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Mutation details: A point mutation of the splice donor site of the intron between exon 25 and exon 26 caused skipping of exon 25 during RNA splicing without disrupting the reading frame. The resulting transcript has a 77 residue deletion. (J:106442)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Lyst Mutation:
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44 strains or lines available |
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| References |
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Original: |
J:106442
Runkel F et al.,
"Grey, a novel mutation in the murine Lyst gene, causes the beige phenotype by skipping of exon 25."
Mamm Genome 2006 Mar;17(3):203-10
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All: |
1 reference(s)
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Analysis Tools
