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| Nomenclature |
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Symbol:
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Tg(CAG-cre/Esr1*)86Lbgn
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Name:
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transgene insertion 86, Laurence Bugeon
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MGI ID: |
MGI:3618929 |
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Synonyms: |
BetaMCM86, Tg(ACTB-cre)86Lbgn, Tg(CAG-cre)86Lbgn, Tg(CAG-cre/ERT)86Lbgn |
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Transgene:
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Tg(CAG-cre/Esr1*)86Lbgn
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x DBA)F1
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Transgene
description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: This transgene expresses cre recombinase as a fusion protein with two copies of a tamoxifen-responsive estrogen receptor under the control of the CMV enhancer/ chicken beta-actin promoter. Expression was detected in a patchy pattern, with the highest levels of expression in skeletal and heart muscle tissue. In kidneys, cre is expressed in the nucleus of podocytes. (J:106338)
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Recombinase activity
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:106338
Bugeon L et al.,
"Inducible gene silencing in podocytes: a new tool for studying glomerular function."
J Am Soc Nephrol 2003 Mar;14(3):786-91
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All: |
2 reference(s)
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Analysis Tools
