|
|
| Nomenclature |
|
Symbol:
|
Chmtm1.2Seab
|
|
Name:
|
choroidermia;
targeted mutation 1.2, Miguel C Seabra
|
|
MGI ID: |
MGI:3617904 |
|
Synonyms: |
Chmnull+Neo |
|
Gene:
|
Chm
Location:
ChrX:113040595-113185517 bp, - strand
Genetic Position: ChrX,
48.94 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:105458
|
|
Parent Cell Line:
| GSI-1 (ES Cell) |
|
Strain of Origin:
|
129X1/SvJ
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Mutation details: Cre expression in the germline produced these mice in which exon 4 was removed and a floxed neomycin-spectinomycin cassette remained. (J:105458)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Chm Mutation:
|
9 strains or lines available |
|
| References |
|
Original: |
J:105458
Tolmachova T et al.,
"Independent degeneration of photoreceptors and retinal pigment epithelium in conditional knockout mouse models of choroideremia."
J Clin Invest 2006 Feb;116(2):386-94
|
|
All: |
1 reference(s)
|
|
Analysis Tools
