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| Nomenclature |
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Symbol:
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Chmtm1.1Seab
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Name:
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choroidermia;
targeted mutation 1.1, Miguel C Seabra
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MGI ID: |
MGI:3617903 |
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Synonyms: |
Chmflox |
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Gene:
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Chm
Location:
ChrX:113040595-113185517 bp, - strand
Genetic Position: ChrX,
48.94 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:105458
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Parent Cell Line:
| GSI-1 (ES Cell) |
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Strain of Origin:
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129X1/SvJ
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Cre expression in the germline produced these mice in which exon 4 was flanked by loxP sites. (J:105458)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Chm Mutation:
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9 strains or lines available |
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| References |
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Original: |
J:105458
Tolmachova T et al.,
"Independent degeneration of photoreceptors and retinal pigment epithelium in conditional knockout mouse models of choroideremia."
J Clin Invest 2006 Feb;116(2):386-94
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All: |
2 reference(s)
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Analysis Tools
