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| Nomenclature |
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Symbol:
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Nfkbiatm1Stw
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Name:
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nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha;
targeted mutation 1, Colin Stewart
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MGI ID: |
MGI:3616190 |
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Gene:
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Nfkbia
Location:
Chr12:55489411-55492647 bp, - strand
Genetic Position: Chr12,
24.0 cM, cytoband C1-C3
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:32527
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Parent Cell Line:
| W9.5/W95 (ES Cell) |
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Strain of Origin:
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129S1/Sv-Oca2+ Tyr+ Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Most of the coding sequence of the gene is replaced by a neomycin selection cassette. (J:32527)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Nfkbia Mutation:
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5 strains or lines available |
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| References |
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Original: |
J:32527
Klement JF et al.,
"IkappaBalpha deficiency results in a sustained NF-kappaB response and severe widespread dermatitis in mice."
Mol Cell Biol 1996 May;16(5):2341-9
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All: |
1 reference(s)
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Analysis Tools
