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| Nomenclature |
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Symbol:
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Arhgdiatm1Ytk
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Name:
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Rho GDP dissociation inhibitor (GDI) alpha;
targeted mutation 1, Yoshimi Takai
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MGI ID: |
MGI:3613573 |
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Synonyms: |
Rho GDIalpha - |
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Gene:
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Arhgdia
Location:
Chr11:120578104-120581624 bp, - strand
Genetic Position: Chr11,
84.29 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:57995
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Parent Cell Line:
| CCE/EK.CCE (ES Cell) |
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Strain of Origin:
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129S/SvEv-Gpi1c
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A 3kb MC1-neomycin resistance cassette replaced all three exons. Western blot analysis did not detect protein in spleen lysates from homozygous mutant mice. (J:57995)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Arhgdia Mutation:
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9 strains or lines available |
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| References |
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Original: |
J:57995
Togawa A et al.,
"Progressive impairment of kidneys and reproductive organs in mice lacking Rho GDIalpha."
Oncogene 1999 Sep 23;18(39):5373-80
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All: |
5 reference(s)
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Analysis Tools
