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| Nomenclature |
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Symbol:
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Cxcr6tm1Litt
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Name:
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chemokine (C-X-C motif) receptor 6;
targeted mutation 1, Daniel Littman
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MGI ID: |
MGI:3613526 |
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Synonyms: |
Bonzo-, Bz-, cxcr6gfp, Cxcr6tm1Unu |
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Gene:
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Cxcr6
Location:
Chr9:123806477-123811754 bp, + strand
Genetic Position: Chr9,
74.57 cM, cytoband F
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:104242
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The coding sequence was replaced with an EGFP. RT-PCR failed to detect transcript in mutants. Strong GFP expression was detected in spleen and lymphoid nodes. (J:104242, J:131925)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:104242
Unutmaz D et al.,
"The primate lentiviral receptor Bonzo/STRL33 is coordinately regulated with CCR5 and its expression pattern is conserved between human and mouse."
J Immunol 2000 Sep 15;165(6):3284-92
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All: |
14 reference(s)
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