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| Nomenclature |
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Symbol:
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Stk11tm1.1Mlfr
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Name:
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serine/threonine kinase 11;
targeted mutation 1.1, Marsha L Frazier
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MGI ID: |
MGI:3612540 |
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Synonyms: |
Lkb1- |
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Gene:
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Stk11
Location:
Chr10:80115803-80130682 bp, + strand
Genetic Position: Chr10,
39.72 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:104347
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Parent Cell Line:
| AB1 (ES Cell) |
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Strain of Origin:
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129S7/SvEvBrd-Hprt+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Intragenic deletion |
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Cre-mediated recombination resulted in the loss of exons 2-8. (J:104347)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Stk11 Mutation:
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5 strains or lines available |
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| References |
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Original: |
J:104347
Wei C et al.,
"Mutation of Lkb1 and p53 genes exert a cooperative effect on tumorigenesis."
Cancer Res 2005 Dec 15;65(24):11297-303
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All: |
5 reference(s)
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Analysis Tools
