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| Nomenclature |
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Symbol:
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Fscn2tm2Sykk
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Name:
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fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus);
targeted mutation 2, Shinji Yokokura
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MGI ID: |
MGI:3612338 |
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Synonyms: |
Fscn2g neo- |
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Gene:
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Fscn2
Location:
Chr11:120361534-120368168 bp, + strand
Genetic Position: Chr11,
84.08 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:103713
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Parent Cell Line:
| J1 (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exon 1 was replaced by GFP. Cre mediated recombination removed a floxed neomycin selection cassette. Fluorescence was detected in the photoreceptors. (J:103713)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Fscn2 Mutation:
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7 strains or lines available |
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| References |
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Original: |
J:103713
Yokokura S et al.,
"Targeted disruption of FSCN2 gene induces retinopathy in mice."
Invest Ophthalmol Vis Sci 2005 Aug;46(8):2905-15
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All: |
1 reference(s)
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Analysis Tools
