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| Nomenclature |
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Symbol:
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Ep300tm3Pkb
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Name:
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E1A binding protein p300;
targeted mutation 3, Paul K Brindle
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MGI ID: |
MGI:3612049 |
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Synonyms: |
p300deltaCH1 |
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Gene:
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Ep300
Location:
Chr15:81586214-81652077 bp, + strand
Genetic Position: Chr15,
38.16 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:103607
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Intragenic deletion |
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Mutation details: The CH1 domain (amino acids 327-378) was excised by homologous recombination. RT-PCR confirmed the deletion in mutant MEFs. (J:103607)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Ep300 Mutation:
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18 strains or lines available |
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| References |
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Original: |
J:103607
Kasper LH et al.,
"Two transactivation mechanisms cooperate for the bulk of HIF-1-responsive gene expression."
EMBO J 2005 Nov 16;24(22):3846-58
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All: |
2 reference(s)
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Analysis Tools
